John Green & Grassroots Activists Pressure Danaher To Drop Price of Tuberculosis Test

Four images: Tuberculosis, John Green, Danaher's GeneXpert Machine, and Activist Typing

Tuberculosis is the world’s deadliest disease — and it is entirely curable.

The airborne disease has plagued human history, and the World Health Organization estimates that 10 million people across the globe are infected by TB every year. Of those millions, 1.6 million still die each year, despite the existence of life-saving technology and medicine. 

These are facts that enrage many — but especially author and philanthropist John Green. 

“Why am I passionate about TB? It’s the deadliest disease in human history, but for most of human history we couldn’t do much about it. However, since the mid-1950s, TB has been curable — yet we still allow TB to kill over 1.6 million people per year,” Green told Good Good Good.

“This is horrifying to me. I don’t want to accept a world where we know how to cure Tuberculosis but deny millions of people access to that cure.” 

This passion was put on display in July of this year. 

Through the social media campaign #PatientsNotPatents, Green and his fanbase —  called Nerdfighters, or Nerdfighteria in collective form — followed the lead of TB advocates to call on drug company Johnson & Johnson to allow the sale of generic bedaquiline — a life-saving TB drug that had been inaccessible under the company’s patent for over a decade.

Nerdfighteria — as well as longtime TB organizations such as the Stop TB Partnership and TB-survivors Phumeza Tisile and Nandita Venkatesan — was successful, and Johnson & Johnson ended its reign on bedaquiline (though advocates are still working to ensure that all low- and middle-income countries receive access to the generic drug).

To end the TB epidemic by 2030 — a goal shared by both the WHO and the United Nations — more pharmaceutical companies need to do their part to make healthcare more accessible, especially in countries with a high TB burden. 

So, in their effort to end TB, Nerdfighteria has taken on a new company: Danaher.

The Issue

Danaher is a multinational corporation, founded by brothers Steven and Mitchell Rales, that owns a number of other large companies, such as Cepheid, Pantone, and X-Rite. (Steven Rales also founded Indian Paintbrush Films, which has financed many of Wes Anderson’s movies.)

Most relevant to this campaign, however, is that in 2006, Danaher and molecular diagnostics company Cepheid created the most helpful diagnostic resource for TB: The GeneXpert machine.

This rapid molecular testing machine is able to test for a number of infectious diseases, including COVID, HIV, TB, and multidrug-resistant TB. In fact, the WHO recommends Xpert tests as the initial test for all people with signs and symptoms of TB

Somebody wearing a gown and white gloves uses a Xpert cartridge in a GeneXpert machine with a USAID logo on it. The GeneXpert machine looks like a large blocky printer.
A GeneXpert device / Photo courtesy of USAID Asia/Flickr (CC BY-NC 2.0)

The GeneXpert machine itself is cost-effective, but its testing cartridges are more costly. The company charges about $10 per regular TB testing cartridge and about $15 per multidrug-resistant TB testing cartridge (though both tests cost the same to manufacture).

According to a 2019 brief from Doctors Without Borders, Danaher and Cepheid could reduce the cost of these cartridges to just $5 each — or lower — based on continuous increases in volume. The brief said a “20-30% reduction in price may be overdue” thanks to expansion in volume.

“These pricing packages serve to expand Cepheid’s footprint … and do nothing to address the urgent need to scale up affordable testing for COVID-19, TB, and other diseases, or to address the longstanding lack of affordability and unfair pricing of Xpert tests,” David Branigan, of activist organization Treatment Action Group, said in a statement in 2021, when Cepheid last updated the pricing of its testing cartridges.

“This is a clear attempt by Cepheid to increase profits without meeting countries’ immediate needs for affordable test cartridges.” 

Green helps contextualize what dropping the cost of the testing cartridges could mean for countries with a high TB burden.

“For countries with high levels of TB, the price of these cartridges is a huge barrier. As one Sierra Leonean lab technician explained to me, ‘These machines are great; if only we could afford the tests,’” Green told Good Good Good.

“Lowering the price of cartridges to $5 would result in millions more people being able to learn they have TB and begin treatment promptly. Hundreds of thousands of lives would be saved over the next decade if Danaher lowered their prices. They know they are overcharging. But it’s essential to put people over profits.”

The Call To Action

Stemming from HIV medication and research efforts since the 1980s and ‘90s, organizations such as Treatment Action Group and Doctors Without Borders have been working on a campaign called Time For $5 since 2019, attempting to convince Danaher to reduce the cost of its Xpert cartridges. 

To increase pressure, Nerdfighteria — which has shown a long-time commitment to philanthropy and global health — is now in on the campaign, too. 

“After seeing what Nerdfighteria helped TB fighters accomplish with Johnson & Johnson, I think we can help [move] the needle with this project,” Nerdfighter community organizer Jessica Dirks told Good Good Good. 

“TB fighters and activists have been working tirelessly to end TB for decades. They understand the problem and what’s needed to address it. What they haven’t had is the support they need behind them, and I hope that we can loudly support their efforts enough to help them succeed.” 

Their call to action? Tell Danher to put people over profit. 

Coinciding with a new video from John Green about the Time For $5 campaign, Nerdfighteria has organized online to get this message to the very top.

Here’s what they’re asking supporters to do:

  • Watch John’s video and visit the community’s website,, to learn about the issue and what activists can do to help. 
  • Call +1-202-828-0850 and respectfully demand that Danaher and Cepheid reduce the cost of TB testing cartridges to $5 each.
  • Respectfully email with the same request. 
  • Post on social media with the hashtags #PeopleOverProfits and #TimeFor5 to spread awareness. (Organizers also encourage users to tag Danaher and Cepheid in their posts and link to research on the campaign)
  • For the more offline folks, Nerdfighter organizers have drafted a letter and other scripts that can be sent to the company, as well.

Just as they did during the Johnson & Johnson campaign, Nerdfighteria has stockpiled custom-made memes for the occasion, spamming Danaher with witty cracks about the company’s practices.

“Danaher’s website says they are a company trying to ‘make the world a healthier, happier place,’” Nerdfighter organizer Nichole Ezell told Good Good Good. “We know they need to make money to stay in business. But we know that they will still make a profit at a $5 price point. We also know people in poverty-stricken countries will die because of this pricing.” 

At the end of the day, Ezell said, Nerdfighteria knows that while corporations can make inhumane choices, they are still made of humans — who hopefully want to do right by others.

“We absolutely want Danaher to be successful and turn a profit so they can continue to manufacture these life-saving machines and components for them,” Ezell said. “We just want as many people to have access to them as possible. That makes the world a healthier, happier place.” 

The Organizers

Nerdfighteria — and John Green himself — have made it clear that this campaign is the work of Treatment Action Group and Doctors Without Borders, and that the years of advocacy by organizations such as the Global Coalition of TB Activists, the Stop TB Partnership, and Global Drug Facility are at the heart of this newly invigorated movement.

But they also seem to know their own power, which includes bringing more passionate advocates into the fold.

Take Elianne, a 22-year-old Nerdfighter in the Netherlands, who has a degree in medicine and will soon wrap up her master’s degree in global health. A longtime Nerdfighter, she has been heavily involved in the organizing of this campaign. 

“I think the power of Nerdfighteria is that all of us — including John and Hank — understand that nothing great like this is ever really a one-person achievement,” Elianne told Good Good Good. “In my experience, being a Nerdfighter has always been about community and using the collective power and talent of that community to make the world a better place.” 

Along with Elianne, countless Nerdfighter organizers worked behind the scenes for weeks leading up to Green’s video to launch a coordinated effort to persuade Danaher to end its over-priced practices. 

“I have tried to use the little expertise I have in the field of global health and medicine to help out where I can. I think that is also why this campaign has worked so well within the community; there are so many people with such a wide range of interests and expertise that we were able to cover all our bases in an incredibly short amount of time,” Elianne continued. 

Leaders in the fanbase have turned from everyday Green devotees to health and business researchers — volunteering hours upon hours to assemble documents, compile research, create visuals, and articulate the perfect wording of their message.

“These are people with real knowledge and experience who are giving it freely and willingly because they want to see this succeed. They want to live in a world without TB,” Dirks said. “If Danaher and Cepheid’s leadership could put the same kind of effort toward making their TB tests affordable to those who need them most, we wouldn’t have to be here right now.” 

But Nerdfighteria is here — thousands of motivated online organizers, following in the footsteps of lifelong TB activists. Together, they unite under the mantra: “We lead by following, and we act with compassion.”

“I am immensely proud of Nerdfighteria’s passion and activism. It’s easy to portray Hank and I as leaders of the community, but the truth is, they’ve led us. They’ve encouraged us to think about how we can use our shared enthusiasm and resources to bring about a better world,” Green told Good Good Good. 

“Our community recognizes that when we listen carefully and work together, we can change the world.” 

It’s that togetherness that fuels their entirely volunteer-led hive. 

“Studying global health can sometimes make you feel a little hopeless about the world and powerless to change it. However, this project has been incredibly uplifting: If enough people pay attention and work together, things can change,” Elianne said. 

“Progress is not inevitable, but neither is inequity. We will be paying attention and working together until real change is achieved.”

As of the time of publication, Danaher has not responded to repeated requests from Good Good Good for comment.

Header montage photo credits — from left to right: USAID Asia/Flickr (CC BY-NC 2.0); vlogbrothers/YouTube (courtesy); Centers for Disease Control and Prevention (Public Domain); corelens/Canva (licensed)

Article Details

September 12, 2023 8:02 AM
September 13, 2023
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